Alejandro Rodríguez-Pena, Jose Manuel Ramos, María Isabel Iglesias, Geert A. Daudey, Antón Leandro Martínez, Jose Manuel Brea Floriani, María Isabel Loza García.
Innopharma Drug Screening and Pharmacogenomics Platform. Centre for Research in Molecular Medicine and Chronic Diseases, University of Santiago de Compostela, 15706 Santiago de Compostela, Spain
In high-throughput screening and sample management, ensuring accuracy, reducing human error, and minimizing manual labour are essential for reliable experimental outcomes. To address these challenges, we have developed a fully automated protocol that integrates advanced robotics with the Echo 650 system. This workflow efficiently manages the entire sample preparation process, from labelling daughter plates with barcodes for identification to dispensing precise volumes of compound stock solutions and adding DMSO with high accuracy. The automated sample handling enables us to host a Public Chemical Library for Spanish / Portuguese academic groups. Chemists can contribute novel compounds and make them available to biological evaluation via this initiative, while biologists can get access to a diversity library with a unique chemical space.
